Drug Information
Drug General Information | |||||
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Drug ID |
D03IUY
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Former ID |
DIB007359
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Drug Name |
Estropipate
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Drug Type |
Small molecular drug
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Indication | Hypogonadism [ICD9: 257.2; ICD10:E23.0, E28.3, E29.1] | Approved | [551871] | ||
Structure |
Download2D MOL |
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Formula |
C22H32N2O5S
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Canonical SMILES |
C[C@]12CC[C@H]3[C@@H](CCc4cc(OS(=O)(=O)O)ccc34)[C@@H]1C<br />CC2=O.C5CNCCN5
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InChI |
1S/C18H22O5S.C4H10N2/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;1-2-6-4-3-5-1/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);5-6H,1-4H2/t14-,15-,16+,18+;/m1./s1
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InChIKey |
HZEQBCVBILBTEP-ZFINNJDLSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Estrogen receptor | Target Info | Modulator | [550912], [551871] | |
Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
Signaling events mediated by HDAC Class II | |||||
Plasma membrane estrogen receptor signaling | |||||
LKB1 signaling events | |||||
Regulation of Telomerase | |||||
ATF-2 transcription factor network | |||||
AP-1 transcription factor network | |||||
FOXM1 transcription factor network | |||||
Validated nuclear estrogen receptor alpha network | |||||
Signaling mediated by p38-alpha and p38-beta | |||||
FOXA1 transcription factor network | |||||
References |
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