Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03IDX
|
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| Drug Name |
WA-8242-A1
|
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| Synonyms |
171272-08-5; 204272-98-0; 204273-00-7; WA-8242-A1; WA-8242-A2; WA-8242-B
|
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| Indication | Unspecified | Investigative | [1], [2] | ||
| Target and Pathway | |||||
| Target(s) | Phospholipase A2 | Target Info | Modulator | ||
| BioCyc Pathway | Phospholipases | ||||
| KEGG Pathway | Glycerophospholipid metabolism | ||||
| Ether lipid metabolism | |||||
| Arachidonic acid metabolism | |||||
| Linoleic acid metabolism | |||||
| alpha-Linolenic acid metabolism | |||||
| Metabolic pathways | |||||
| Ras signaling pathway | |||||
| Vascular smooth muscle contraction | |||||
| Pancreatic secretion | |||||
| Fat digestion and absorption | |||||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
| Reactome | Acyl chain remodelling of PC | ||||
| Acyl chain remodelling of PE | |||||
| Acyl chain remodelling of PI | |||||
| WikiPathways | Glycerophospholipid biosynthesis | ||||
| References | |||||
| REF 1 | WA8242A1, A2 and B, novel secretary phospholipase A2 inhibitors produced by Streptomyces violaceusniger.III.Structure elucidation and total synthesis of WA8242B.J Antibiot (Tokyo). | ||||
| REF 2 | WA8242A1, A2 and B, novel secretory phospholipase A2 inhibitors produced by Streptomyces violaceusniger.I.Taxonomy, production and purification.J Antibiot (Tokyo). | ||||
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