Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03HCZ
|
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| Drug Name |
Propoxyphene Hydrochloride
|
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| Synonyms |
Darvon; Dolene; Kesso-gesic; Prophene 65; Propoxyphene Hydrochloride; Propoxyphene Hydrochloride 65; Darvon-n; Propoxyphene Napsylate
|
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| Drug Type |
Small molecular drug
|
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| Indication | Mild pain [ICD10:R52, G89] | Approved | [1] | ||
| Therapeutic Class |
Neurology Agents
|
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| Company |
Xanodyne Pharmaceutics Inc
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C22H30ClNO2
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Mu-type opioid receptor | Target Info | Modulator | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Estrogen signaling pathway | |||||
| Morphine addiction | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin release | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | TCR Signaling Pathway | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| Peptide GPCRs | |||||
| Opioid Signalling | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
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