Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03GYK
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| Former ID |
DPR000067
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| Drug Name |
Laropiprant+niacin
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| Synonyms |
Tredaptive (TN)
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| Drug Type |
Small molecular drug
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| Indication | Dyslipidaemias [ICD9: 272; ICD10:E78] | Discontinued in Phase 3 | [522926] | ||
| Company |
Merck
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| Structure |
|
Download2D MOL |
|||
| Formula |
C27H24ClFN2O6S
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| Canonical SMILES |
CS(=O)(=O)C1=C2C(=CC(=C1)F)C3=C(N2CC4=CC=C(C=C4)Cl)C(CC<br />3)CC(=O)O.C1=CC(=CN=C1)C(=O)O
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| InChI |
1S/C21H19ClFNO4S.C6H5NO2/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12;8-6(9)5-2-1-3-7-4-5/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26);1-4H,(H,8,9)/t13-;/m1./s1
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| InChIKey |
ZZRFQBQNZLFESZ-BTQNPOSSSA-N
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| CAS Number |
CAS 571170-77-9
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| SuperDrug ATC ID |
C04AC01
|
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| SuperDrug CAS ID |
cas=000059676
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| Target and Pathway | |||||
| Target(s) | Prostaglandin D2 receptor | Target Info | Antagonist | [536740] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Pathway Interaction Database | Thromboxane A2 receptor signaling | ||||
| PathWhiz Pathway | Intracellular Signalling Through PGD2 receptor and Prostaglandin D2 | ||||
| References | |||||
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