Drug General Information
Drug ID	D03GAX
Former ID	DIB000037
Drug Name	TAK-802
Indication	Urinary dysfunction [ICD10:N39.3-N39.4]		Discontinued in Phase 2	[547886]
Company	Takeda Pharmaceutical Co Ltd
Structure		Download 2D MOL 3D MOL
Canonical SMILES	N12c3c(cc(cc3CCC1=O)C(=O)CCC1CCN(Cc3cc(F)ccc3)CC1)CC2
Target and Pathway
Target(s)	Acetylcholinesterase	Target Info	Inhibitor	[526952]
KEGG Pathway	Glycerophospholipid metabolism
	Cholinergic synapse
PANTHER Pathway	Muscarinic acetylcholine receptor 1 and 3 signaling pathway
	Muscarinic acetylcholine receptor 2 and 4 signaling pathway
	Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database	ATF-2 transcription factor network
PathWhiz Pathway	Phospholipid Biosynthesis
WikiPathways	Monoamine Transport
	Biogenic Amine Synthesis
	Acetylcholine Synthesis
	Integrated Pancreatic Cancer Pathway
References
Ref 547886	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020145)
Ref 526952	Effects of TAK-802, a novel acetylcholinesterase inhibitor, on distension-induced rhythmic bladder contractions in rats and guinea pigs. Eur J Pharmacol. 2004 Feb 6;485(1-3):299-305.

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