Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03GAX
|
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| Former ID |
DIB000037
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| Drug Name |
TAK-802
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| Indication | Urinary dysfunction [ICD10:N39.3-N39.4] | Discontinued in Phase 2 | [1] | ||
| Company |
Takeda Pharmaceutical Co Ltd
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
N12c3c(cc(cc3CCC1=O)C(=O)CCC1CCN(Cc3cc(F)ccc3)CC1)CC2
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| Target and Pathway | |||||
| Target(s) | Acetylcholinesterase | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Glycerophospholipid metabolism | ||||
| Cholinergic synapse | |||||
| PANTHER Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | ||||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||||
| Nicotinic acetylcholine receptor signaling pathway | |||||
| Pathway Interaction Database | ATF-2 transcription factor network | ||||
| PathWhiz Pathway | Phospholipid Biosynthesis | ||||
| WikiPathways | Monoamine Transport | ||||
| Biogenic Amine Synthesis | |||||
| Acetylcholine Synthesis | |||||
| Integrated Pancreatic Cancer Pathway | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020145) | ||||
| REF 2 | Effects of TAK-802, a novel acetylcholinesterase inhibitor, on distension-induced rhythmic bladder contractions in rats and guinea pigs. Eur J Pharmacol. 2004 Feb 6;485(1-3):299-305. | ||||
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