| Drug General Information |
| Drug ID |
D03FZG
|
| Former ID |
DNC000910
|
| Drug Name |
LY-593039
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Target and Pathway |
| Target(s) |
Muscarinic acetylcholine receptor M1 |
Target Info |
Agonist |
[1]
|
|---|
|
KEGG Pathway
|
Calcium signaling pathway
|
|
cAMP signaling pathway
|
|
Neuroactive ligand-receptor interaction
|
|
PI3K-Akt signaling pathway
|
|
Cholinergic synapse
|
|
Regulation of actin cytoskeleton
|
|
PANTHER Pathway
|
Alzheimer disease-amyloid secretase pathway
|
|
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
|
|
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
|
|
Reactome
|
Muscarinic acetylcholine receptors
|
|
G alpha (q) signalling events
|
|
WikiPathways
|
Monoamine GPCRs
|
|
Calcium Regulation in the Cardiac Cell
|
|
Regulation of Actin Cytoskeleton
|
|
GPCRs, Class A Rhodopsin-like
|
|
Gastrin-CREB signalling pathway via PKC and MAPK
|
|
Secretion of Hydrochloric Acid in Parietal Cells
|
|
GPCR ligand binding
|
|
GPCR downstream signaling
|
| References |
| REF 1 | Pharmacological comparison of muscarinic ligands: historical versus more recent muscarinic M1-preferring receptor agonists. Eur J Pharmacol. 2009 Mar 1;605(1-3):53-6. Epub 2009 Jan 11. |
|---|
