Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03EGA
|
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| Former ID |
DIB020988
|
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| Drug Name |
SRT1720
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [529184] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C25H23N7OS
|
||||
| InChI |
InChI=1S/C25H23N7OS/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31/h1-8,13,15-16,26H,9-12,14H2,(H,29,33)
|
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| InChIKey |
IASPBORHOMBZMY-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
48412536, 56072363, 99460882, 103563410, 104097840, 124893771, 124893772, 141483860, 152258247, 160647083, 160825152, 162158018, 162202784, 163092466, 163384436, 163840337, 165236819, 170559104, 172088859, 173019921, 186014828, 188899577, 198992051, 202562382, 204366497, 223366036, 223592782, 227223342, 244838855, 252216338, 252303031, 252451835, 252490903
|
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| Target and Pathway | |||||
| Target(s) | NAD-dependent deacetylase sirtuin-1 | Target Info | Activator | [529184] | |
| PANTHER Pathway | p53 pathway | ||||
| Pathway Interaction Database | p73 transcription factor network | ||||
| Signaling events mediated by HDAC Class III | |||||
| E2F transcription factor network | |||||
| HIF-2-alpha transcription factor network | |||||
| Signaling events mediated by HDAC Class I | |||||
| FoxO family signaling | |||||
| Regulation of Androgen receptor activity | |||||
| Regulation of retinoblastoma protein | |||||
| References | |||||
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