Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02ZKR
|
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| Former ID |
DNC008301
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| Drug Name |
BCX-3408
|
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| Synonyms |
R-3421
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Phase 2 | [522068] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C12H16N4O3
|
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| Canonical SMILES |
C1C(C(CN1CC2=CNC3=C2NC=NC3=O)O)CO
|
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| InChI |
1S/C12H16N4O3/c17-5-8-3-16(4-9(8)18)2-7-1-13-11-10(7)14-6-15-12(11)19/h1,6,8-9,13,17-18H,2-5H2,(H,14,15,19)/t8-,9+/m1/s1
|
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| InChIKey |
AFNHHLILYQEHKK-BDAKNGLRSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Purine nucleoside phosphorylase | Target Info | Inhibitor | [529290] | |
| BioCyc Pathway | Arsenate detoxification I (glutaredoxin) | ||||
| Purine nucleotides degradation | |||||
| Urate biosynthesis/inosine 5'-phosphate degradation | |||||
| Purine deoxyribonucleosides degradation | |||||
| Purine ribonucleosides degradation to ribose-1-phosphate | |||||
| Guanosine nucleotides degradation | |||||
| Adenosine nucleotides degradation | |||||
| Superpathway of purine nucleotide salvage | |||||
| Adenine and adenosine salvage III | |||||
| Guanine and guanosine salvage | |||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| EGFR1 Signaling Pathway | |||||
| PathWhiz Pathway | Purine Metabolism | ||||
| Nicotinate and Nicotinamide Metabolism | |||||
| Reactome | Purine salvage | ||||
| Purine catabolism | |||||
| References | |||||
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