Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02YNH
|
||||
| Former ID |
DIB002867
|
||||
| Drug Name |
CP-809101
|
||||
| Synonyms |
CP-809101; PF-3246799; PHA-181731A; PHA-57378; PHA-670080; PNU-181731A; PNU-57378; PNU-57378E; 5-HT 2 agonists, Pharmacia
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Neurological disease [ICD9: 338, 338.2, 410, 782.3,780; ICD10:I21, I22, R52, R52.1-R52.2, R60.9, G89] | Investigative | [1] | ||
| Company |
Pharmacia Corp
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C15H17ClN4O
|
||||
| Canonical SMILES |
N1CCc2c(CC1)cnc(n2)Cc1ccccc1
|
||||
| CAS Number |
CAS 364344-56-9
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 2C receptor | Target Info | Agonist | [1] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gap junction | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| PANTHER Pathway | 5HT2 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | ||||
| G alpha (q) signalling events | |||||
| WikiPathways | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 8). | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.