Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02XOK
|
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| Former ID |
DNCL003097
|
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| Drug Name |
Levomilnacipran
|
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| Drug Type |
Small molecular drug
|
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| Indication | Fibromyalgia [ICD9: 729.1; ICD10:M79.7] | Approved | [1], [2] | ||
| Company |
Forest Laboratories
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C15H22N2O
|
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| InChI |
InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3/t13-,15+/m0/s1
|
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| InChIKey |
GJJFMKBJSRMPLA-DZGCQCFKSA-N
|
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| CAS Number |
CAS 96847-55-1
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Sodium-dependent noradrenaline transporter | Target Info | Modulator | [1] | |
| Sodium-dependent serotonin transporter | Target Info | Modulator | [1] | ||
| KEGG Pathway | Serotonergic synapse | ||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway | ||||
| 5HT2 type receptor mediated signaling pathway | |||||
| 5HT3 type receptor mediated signaling pathway | |||||
| 5HT4 type receptor mediated signaling pathway | |||||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | ||||
| WikiPathways | Monoamine Transport | ||||
| NRF2 pathway | |||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport | |||||
| SIDS Susceptibility Pathways | |||||
| Synaptic Vesicle Pathway | |||||
| Serotonin Transporter Activity | |||||
| References | |||||
| REF 1 | Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92. | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7435). | ||||
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