Drug Information

Drug General Information
Drug ID
D02WQR
Former ID
DIB012808
Drug Name
GSK-008A
Synonyms
GSK-008A; Progesterone receptor agonists (gynecological disorder); Progesterone receptor agonists (gynecological disorder), GSK
Indication Gynecological disorder [ICD10:N70-N98] Investigative [543903]
Company
GlaxoSmithKline plc
Structure
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2D MOL

3D MOL
Canonical SMILES
c1n(c(nn1)C(N(c1ccc(c(c1)Cl)C#N)Cc1c(cccc1)Cl)C)C
Target and Pathway
Target(s) Progesterone receptor Target Info Agonist [543903]
KEGG Pathway Oocyte meiosis
Progesterone-mediated oocyte maturation
Pathway Interaction Database Cellular roles of Anthrax toxin
Reactome Nuclear signaling by ERBB4
Nuclear Receptor transcription pathway
WikiPathways Ovarian Infertility Genes
Signaling by ERBB4
Nuclear Receptors
References
Ref 543903(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 627).
Ref 543903(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 627).

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