TTD | Drug: D02TXW

Drug General Information
Drug ID	D02TXW
Former ID	DIB019044
Drug Name	BX 667
Synonyms	BX-667; BX667
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539117]
Structure		Download 2D MOL
Formula	C29H38N4O9
InChI	InChI=1S/C29H38N4O9/c1-6-40-27(38)29(4,5)42-23-17-22(30-21-16-18(3)8-9-19(21)23)25(36)31-20(10-11-24(34)35)26(37)32-12-14-33(15-13-32)28(39)41-7-2/h8-9,16-17,20H,6-7,10-15H2,1-5H3,(H,31,36)(H,34,35)/t20-/m0/s1
InChIKey	PHDMSNZRDFPYNQ-FQEVSTJZSA-N
PubChem Compound ID	16681707
PubChem Substance ID	26657363, 30547552, 80956011, 135650046, 163338450, 163346227
Target and Pathway
Target(s)	P2Y purinoceptor 12	Target Info	Antagonist	[529525]
KEGG Pathway	Platelet activation
Reactome	P2Y receptors
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539117	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1767).
Ref 529525	Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): pharmacodynamic and pharmacokinetic characterization. Thromb Res. 2008;122(4):533-40.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information