Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02TSN
|
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| Former ID |
DIB018925
|
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| Drug Name |
AZ20
|
||||
| Synonyms |
AZ-20; AZ 20; compound 6 [PMID: 46244454]
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [532224] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C21H24N4O3S
|
||||
| InChI |
InChI=1S/C21H24N4O3S/c1-14-13-28-11-10-25(14)19-12-18(21(7-8-21)29(2,26)27)23-20(24-19)16-4-3-5-17-15(16)6-9-22-17/h3-6,9,12,14,22H,7-8,10-11,13H2,1-2H3/t14-/m1/s1
|
||||
| InChIKey |
SCGCBAAYLFTIJU-CQSZACIVSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Serine threonine protein kinase ATR | Target Info | Inhibitor | [532224] | |
| PANTHER Pathway | p53 pathway | ||||
| p53 pathway feedback loops 2 | |||||
| Pathway Interaction Database | Fanconi anemia pathway | ||||
| ATR signaling pathway | |||||
| Signaling events mediated by TCPTP | |||||
| Circadian rhythm pathway | |||||
| BARD1 signaling events | |||||
| p53 pathway | |||||
| Reactome | Meiotic synapsis | ||||
| Activation of ATR in response to replication stress | |||||
| Regulation of HSF1-mediated heat shock response | |||||
| HDR through Single Strand Annealing (SSA) | |||||
| Processing of DNA double-strand break ends | |||||
| Presynaptic phase of homologous DNA pairing and strand exchange | |||||
| G2/M DNA damage checkpoint | |||||
| References | |||||
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