Drug General Information
Drug ID	D02TLZ
Former ID	DNC011681
Drug Name	3-Biphenyl-4-yl-N-hydroxy-N-methyl-acrylamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[532087]
Structure		Download 2D MOL 3D MOL
Formula	C16H15NO2
Canonical SMILES	CN(C(=O)C=CC1=CC=C(C=C1)C2=CC=CC=C2)O
InChI	1S/C16H15NO2/c1-17(19)16(18)12-9-13-7-10-15(11-8-13)14-5-3-2-4-6-14/h2-12,19H,1H3/b12-9+
InChIKey	TUEHLNCQVBWQNV-FMIVXFBMSA-N
PubChem Compound ID	13746840
Target and Pathway
Target(s)	Arachidonate 5-lipoxygenase	Target Info	Inhibitor	[532087]
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 532087	J Med Chem. 1990 Mar;33(3):992-8.Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.
Ref 532087	J Med Chem. 1990 Mar;33(3):992-8.Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.

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