TTD | Drug: D02SNU

Drug General Information
Drug ID	D02SNU
Former ID	DIB020517
Drug Name	NE97220
Synonyms	NE 97220; CGA 103586; Q 332
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540155]
Structure		Download 2D MOL
Formula	C7H12N2O6P2
InChI	InChI=1S/C7H12N2O6P2/c1-5-3-2-4-8-6(5)9-7(16(10,11)12)17(13,14)15/h2-4,7H,1H3,(H,8,9)(H2,10,11,12)(H2,13,14,15)
InChIKey	NAIJOBGUXRHQJW-UHFFFAOYSA-N
PubChem Compound ID	5276531
PubChem Substance ID	15617816, 23941377, 39285961, 56310607, 79727958, 103240370, 103995448, 113842674, 135650704, 233700408, 249552380, 249818654
Target and Pathway
Target(s)	Farnesyl pyrophosphatesynthetase	Target Info	Inhibitor	[529362]
KEGG Pathway	Terpenoid backbone biosynthesis
	Metabolic pathways
	Biosynthesis of antibiotics
	Influenza A
	HTLV-I infection
PathWhiz Pathway	Steroid Biosynthesis
Reactome	Cholesterol biosynthesis
Reactome	Activation of gene expression by SREBF (SREBP)
WikiPathways	Activation of Gene Expression by SREBP (SREBF)
	SREBP signalling
	Cholesterol Biosynthesis
References
Ref 540155	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3171).
Ref 529362	J Med Chem. 2008 Apr 10;51(7):2187-95. Epub 2008 Mar 8.Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase.

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Drug Information