Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02RZC
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| Former ID |
DIB005760
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| Drug Name |
ASC-JMX2
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| Synonyms |
ASC-JMX2; ASCJ-M12; ASCJ-M5; Q-103; Q-49; Androgen antagonist (prostate tumor/benign prostatic hyperplasia), AndroScience; ARD enhancers (oral, prostate tumor/benign prostatic hyperplasia), AndroScience
|
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| Indication | Prostate hyperplasia [ICD10:N40] | Investigative | [1] | ||
| Company |
AndroScience Corp
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
C(=C\c1ccc(c(c1)OC)OC)/C(=O)C1C(=O)CC(C1)(C(C(=O)/C=C/c<br />1cc(c(cc1)OC)OC)C(=O)/C=C/c1ccc(c(c1)OC)OC)c1cc(c(cc1)O<br />C)OC
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| Target and Pathway | |||||
| Target(s) | Androgen receptor | Target Info | Antagonist | [1] | |
| KEGG Pathway | Oocyte meiosis | ||||
| Pathways in cancer | |||||
| Prostate cancer | |||||
| NetPath Pathway | EGFR1 Signaling Pathway | ||||
| AndrogenReceptor Signaling Pathway | |||||
| FSH Signaling Pathway | |||||
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Coregulation of Androgen receptor activity | |||||
| Regulation of Androgen receptor activity | |||||
| Nongenotropic Androgen signaling | |||||
| Regulation of nuclear beta catenin signaling and target gene transcription | |||||
| FOXA1 transcription factor network | |||||
| Notch-mediated HES/HEY network | |||||
| Reactome | Nuclear Receptor transcription pathway | ||||
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | |||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Integrated Pancreatic Cancer Pathway | |||||
| Prostate Cancer | |||||
| Integrated Breast Cancer Pathway | |||||
| Nuclear Receptors | |||||
| Androgen receptor signaling pathway | |||||
| References | |||||
| REF 1 | The ChEMBL database in 2017. | ||||
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