Drug Information

Drug General Information
Drug ID
D02OZY
Former ID
DAP000675
Drug Name
Metharbital
Synonyms
Endiemal; Endiemalum; Gemonal; Gemonil; Gemonit; Metabarbital; Metarbital; Metarbitale; Methabarbital; Methabarbitone; Metharbitalum; Metharbitone; Metharbutal; Methylbarbital; Metarbitale [DCIT]; AN 23; Sch 412; Gemonil (TN); Metarbital [INN-Spanish]; Metharbital [INN:JAN]; Metharbitalum [INN-Latin]; N-Methylbarbital; Metharbital (JAN/INN); 1-Methylbarbital; 5,5-Diethyl-1-methyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5,5-Diethyl-1-methylbarbituric acid; 5,5-diethyl-1-methyl-1,3-diazinane-2,4,6-trione; 5,5-diethyl-1-methylpyrimidine-2,4,6(1H,3H,5H)-trione
Drug Type
Small molecular drug
Indication Epilepsy [ICD10:G40] Approved [538407], [542246]
Therapeutic Class
Anticonvulsants
Company
Abbott Laboratories
Structure
Download
2D MOL

3D MOL
Formula
C9H14N2O3
InChI
InChI=1S/C9H14N2O3/c1-4-9(5-2)6(12)10-8(14)11(3)7(9)13/h4-5H2,1-3H3,(H,10,12,14)
InChIKey
FWJKNZONDWOGMI-UHFFFAOYSA-N
CAS Number
CAS 50-11-3
PubChem Compound ID
4099
PubChem Substance ID
87762, 5065190, 7848445, 8152571, 10524269, 15219977, 29223208, 46508167, 48416239, 49874134, 50125862, 57322141, 71931286, 75934082, 103165910, 104305425, 125823562, 127909218, 132522175, 134337964, 134971003, 137004936, 140085464, 144206305, 160963809, 163263703, 164845527, 177513113, 178103804, 179116777, 198967192, 226458080, 249543436, 250037661, 252351626
SuperDrug ATC ID
N03AA30
SuperDrug CAS ID
cas=000050113
Target and Pathway
Target(s) GABA A receptor Target Info Modulator [556264]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 538407FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 008322.
Ref 542246(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7230).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.