Drug General Information
Drug ID
D02LCR
Former ID
DNC001444
Drug Name
Tiapride
Drug Type
Small molecular drug
Indication Alcohol use disorders [ICD9: 303; ICD10:F10.2] Approved [551871]
Structure
Download
2D MOL

3D MOL

Formula
C15H24N2O4S
Canonical SMILES
CCN(CC)CCNC(=O)C1=C(C=CC(=C1)S(=O)(=O)C)OC
InChI
1S/C15H24N2O4S/c1-5-17(6-2)10-9-16-15(18)13-11-12(22(4,19)20)7-8-14(13)21-3/h7-8,11H,5-6,9-10H2,1-4H3,(H,16,18)
InChIKey
JTVPZMFULRWINT-UHFFFAOYSA-N
CAS Number
CAS 51012-32-9
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
N05AL03
SuperDrug CAS ID
cas=051012329
Target and Pathway
Target(s) D(2) dopamine receptor Target Info Antagonist [535493]
KEGG Pathway Rap1 signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Alcoholism
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
References
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 535493The treatment of Tourette's syndrome: current opinions. Expert Opin Pharmacother. 2002 Jul;3(7):899-914.

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