Drug Information

Drug General Information
Drug ID
D02KMO
Former ID
DAP001417
Drug Name
Pinacidil
Synonyms
Pinacidilum; P 1134; S 1230; P-154; Pinacidil (anhydrous); Pinacidilum [INN-Latin]; S-1230; N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)guanidine; Guanidine, 2-cyano-3-(4-pyridyl)-1-(1,2,2-trimethylpropyl)-, monohydrate; Guanidine, N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-, monohydrate; (+-)-Pinacidil; (+/-)-N-Cyano-N'-4-pyridinyl-N"-(1,2,2-trimethylpropyl)guanidine; (R,S)-Pinacidil; (inverted question mark)-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-guanidine; 1-cyano-2-(3,3-dimethylbutan-2-yl)-3-pyridin-4-ylguanidine; 2-Cyano-3-(4-pyridinyl)-1-(1,2,2-trimethylpropyl)guanidine; 2-Cyano-3-(4-pyridyl)-1-(1,2,2-trimethylpropyl)guanidine monohydrate
Drug Type
Small molecular drug
Indication High blood pressure [ICD9: 401; ICD10:I10-I16] Approved [538525], [539542]
Therapeutic Class
Antihypertensive Agents
Structure
Download
2D MOL

3D MOL
Formula
C13H19N5
InChI
InChI=1S/C13H19N5/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11/h5-8,10H,1-4H3,(H2,15,16,17,18)
InChIKey
IVVNZDGDKPTYHK-UHFFFAOYSA-N
CAS Number
CAS 85371-64-8
PubChem Compound ID
4826
PubChem Substance ID
4669683, 8152962, 10321422, 11120045, 11120533, 11121021, 11121526, 11122006, 11147128, 11342030, 11362213, 11362595, 11363281, 11365157, 11365843, 11367719, 11368405, 11370461, 11370462, 11373320, 11375881, 11376567, 11466274, 11467394, 11485554, 11485987, 11487615, 11489555, 11494201, 11532877, 14892701, 15196571, 17405595, 24277866, 26613193, 26679753, 26749106, 26749107, 26752205, 26752206, 29223908, 47425317, 47721339, 47721634, 47944819, 47944820, 48019685, 48020021, 48170469, 48244097
SuperDrug ATC ID
C02DG01
SuperDrug CAS ID
cas=085371648
Target and Pathway
Target(s) Potassium channel Target Info Modulator [556264]
References
Ref 538525FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 019456.
Ref 539542(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2412).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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