Drug Information
Drug General Information | |||||
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Drug ID |
D02KKQ
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Former ID |
DIB008462
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Drug Name |
BAM-1110
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Synonyms |
(6aR,9R,10aR)-7-Methyl-9-(1,2,4-triazol-1-ylmethyl)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolinemaleate
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Drug Type |
Small molecular drug
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Indication | Parkinson's disease [ICD9: 332; ICD10:G20] | Discontinued in Phase 2 | [545888] | ||
Structure |
Download2D MOL |
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Formula |
C18H21N5
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Canonical SMILES |
CN1CC(CC2C1CC3=CNC4=CC=CC2=C34)CN5C=NC=N5
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InChI |
1S/C18H21N5/c1-22-8-12(9-23-11-19-10-21-23)5-15-14-3-2-4-16-18(14)13(7-20-16)6-17(15)22/h2-4,7,10-12,15,17,20H,5-6,8-9H2,1H3/t12-,15?,17-/m1/s1
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InChIKey |
AIBHLZVVPXCTKY-XURPUJGUSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Dopamine D1 receptor | Target Info | Modulator | ||
D(2) dopamine receptor | Target Info | Modulator | |||
PANTHER Pathway | Dopamine receptor mediated signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
Dopamine receptor mediated signaling pathway | |||||
Nicotine pharmacodynamics pathway | |||||
PathWhiz Pathway | Dopamine Activation of Neurological Reward System | ||||
WikiPathways | Hypothetical Network for Drug Addiction | ||||
Monoamine GPCRs | |||||
GPCRs, Class A Rhodopsin-like | |||||
Genes and (Common) Pathways Underlying Drug Addiction | |||||
GPCR ligand binding | |||||
GPCR downstream signalingWP666:Hypothetical Network for Drug Addiction | |||||
GPCR downstream signaling | |||||
Nicotine Activity on Dopaminergic Neurons | |||||
References |
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