Drug Information

Drug General Information
Drug ID
D02ITL
Former ID
DIB008201
Drug Name
AV-201
Synonyms
AAV (amino acid decarboxylase), Avigen; AAV (tyrosine hydroxylase), Avigen; AAV gene therapy (Parkinsons), Avigen; AAV vector (AADC), Avigen; AAV vector (TH), Avigen; AAV-hAADC-2; Gene therapy (PD), Avigen; Gene therapy (Parkinsons disease), Avigen; Gene therapy (L-aromatic amino acid decarboxylase), Avigen
Indication Parkinson's disease [ICD9: 332; ICD10:G20] Phase 2 [551892]
Company
Avigen Inc
Target and Pathway
Target(s) Aromatic-L-amino-acid decarboxylase Target Info Modulator
BioCyc Pathway Superpathway of tryptophan utilization
Tryptophan degradation via tryptamine
Serotonin and melatonin biosynthesis
Catecholamine biosynthesis
KEGG Pathway Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
Tryptophan metabolism
Metabolic pathways
Serotonergic synapse
Dopaminergic synapse
Cocaine addiction
Amphetamine addiction
Alcoholism
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
5-Hydroxytryptamine biosynthesis
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
PathWhiz Pathway Catecholamine Biosynthesis
Tyrosine Metabolism
Tryptophan Metabolism
WikiPathways SIDS Susceptibility Pathways
Biogenic Amine Synthesis
Tryptophan metabolism
Dopaminergic Neurogenesis
Metabolism of amino acids and derivatives
Dopamine metabolism
Parkinsons Disease Pathway
Nicotine Activity on Dopaminergic Neurons
References
Ref 551892Clinical pipeline report, company report or official report of Genzyme.

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