Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D02EWM
|
||||
Former ID |
DNC005941
|
||||
Drug Name |
(R)-sirtinol
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Discovery agent | Investigative | [527886] | ||
Structure |
Download2D MOL |
||||
Formula |
C26H22N2O2
|
||||
Canonical SMILES |
CC(C1=CC=CC=C1)NC(=O)C2=CC=CC=C2NC=C3C(=O)C=CC4=CC=CC=C<br />43
|
||||
InChI |
1S/C26H22N2O2/c1-18(19-9-3-2-4-10-19)28-26(30)22-13-7-8-14-24(22)27-17-23-21-12-6-5-11-20(21)15-16-25(23)29/h2-18,27H,1H3,(H,28,30)/b23-17-/t18-/m1/s1
|
||||
InChIKey |
YUGODMKHHCZZOI-CNGOPUHISA-N
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | NAD-dependent deacetylase sirtuin-1 | Target Info | Inhibitor | [527886] | |
PANTHER Pathway | p53 pathway | ||||
Pathway Interaction Database | p73 transcription factor network | ||||
Signaling events mediated by HDAC Class III | |||||
E2F transcription factor network | |||||
HIF-2-alpha transcription factor network | |||||
Signaling events mediated by HDAC Class I | |||||
FoxO family signaling | |||||
Regulation of Androgen receptor activity | |||||
Regulation of retinoblastoma protein | |||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.