TTD | Drug: D02DPK

Drug General Information
Drug ID	D02DPK
Former ID	DIB020022
Drug Name	hyp 9
Synonyms	2,4-(1-keto-hexyl) phloroglucinol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540699]
Structure		Download 2D MOL
Formula	C18H26O5
InChI	InChI=1S/C18H26O5/c1-3-5-7-9-12(19)16-14(21)11-15(22)17(18(16)23)13(20)10-8-6-4-2/h11,21-23H,3-10H2,1-2H3
InChIKey	JRHOSBCIYWDGHN-UHFFFAOYSA-N
PubChem Compound ID	15659415
PubChem Substance ID	90326623, 103185720, 128316271, 162248806, 178100924, 235123433
Target and Pathway
Target(s)	Short transient receptor potential channel 6	Target Info	Activator	[530580]
PANTHER Pathway	Alzheimer disease-presenilin pathway
Pathway Interaction Database	Endothelins
	Nephrin/Neph1 signaling in the kidney podocyte
	EPO signaling pathway
	PAR1-mediated thrombin signaling events
Reactome	Effects of PIP2 hydrolysis
	TRP channels
	Role of second messengers in netrin-1 signaling
WikiPathways	Primary Focal Segmental Glomerulosclerosis FSGS
	Platelet homeostasis
	Netrin-1 signaling
	GPCR downstream signaling
	Effects of PIP2 hydrolysis
References
Ref 540699	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4101).
Ref 530580	Simple 2,4-diacylphloroglucinols as classic transient receptor potential-6 activators--identification of a novel pharmacophore. Mol Pharmacol. 2010 Mar;77(3):368-77.

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Drug Information