| Drug General Information |
| Drug ID |
D02DHC
|
| Former ID |
DNC002526
|
| Drug Name |
Methyltrienolone
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Formula |
C19H24O2
|
| InChI |
InChI=1S/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/m1/s1
|
| InChIKey |
CCCIJQPRIXGQOE-XWSJACJDSA-N
|
| CAS Number |
CAS 965-93-5
|
| PubChem Compound ID |
|
| PubChem Substance ID |
398773, 584879, 584893, 837854, 837858, 841908, 7847067, 7890182, 7980478, 8026845, 9403921, 41282429, 46393581, 46393820, 46505539, 53787860, 56310809, 56311157, 56312148, 56312608, 56312612, 56312613, 56312615, 56312617, 56314009, 56314290, 57288539, 57400754, 75158741, 87351148, 103097923, 103423764, 104133382, 104471746, 126644318, 127603464, 135650595, 151979689, 160847018, 160966155, 170506536, 178100455, 179316929, 198977476, 208011852, 223436519, 223554873, 223694040, 226487263, 241169794
|
| Target and Pathway |
| Target(s) |
Progesterone receptor |
Target Info |
Inhibitor |
[2]
|
|---|
| Androgen receptor |
Target Info |
Inhibitor |
[2]
|
|
KEGG Pathway
|
Oocyte meiosis
|
|
Progesterone-mediated oocyte maturationhsa04114:Oocyte meiosis
|
|
Pathways in cancer
|
|
Prostate cancer
|
|
NetPath Pathway
|
EGFR1 Signaling Pathway
|
|
AndrogenReceptor Signaling Pathway
|
|
FSH Signaling Pathway
|
|
Pathway Interaction Database
|
Cellular roles of Anthrax toxinsmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
|
|
Coregulation of Androgen receptor activity
|
|
Regulation of Androgen receptor activity
|
|
Nongenotropic Androgen signaling
|
|
Regulation of nuclear beta catenin signaling and target gene transcription
|
|
FOXA1 transcription factor network
|
|
Notch-mediated HES/HEY network
|
|
Reactome
|
Nuclear signaling by ERBB4
|
|
Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway
|
|
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
|
|
WikiPathways
|
Ovarian Infertility Genes
|
|
Signaling by ERBB4
|
|
Nuclear ReceptorsWP706:SIDS Susceptibility Pathways
|
|
Integrated Pancreatic Cancer Pathway
|
|
Prostate Cancer
|
|
Integrated Breast Cancer Pathway
|
|
Nuclear Receptors
|
|
Androgen receptor signaling pathway
|
| References |
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2857). |
|---|
| REF 2 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
