Drug Information
Drug General Information | |||||
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Drug ID |
D02CZK
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Former ID |
DNCL002635
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Drug Name |
Karenitecin
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Synonyms |
Karenitecin (TN)
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Drug Type |
Small molecular drug
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Indication | Advanced ovarian cancer; Lung cancer [ICD9: 183, 162; ICD10:C56, C33-C34] | Phase 3 | [522031] | ||
Company |
BioNumerik Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C25H28N2O4Si
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Canonical SMILES |
CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)CC[S<br />i](C)(C)C)O
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InChI |
1S/C25H28N2O4Si/c1-5-25(30)19-12-21-22-17(13-27(21)23(28)18(19)14-31-24(25)29)15(10-11-32(2,3)4)16-8-6-7-9-20(16)26-22/h6-9,12,30H,5,10-11,13-14H2,1-4H3/t25-/m0/s1
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InChIKey |
POADTFBBIXOWFJ-VWLOTQADSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Toposisomerase-1 | Target Info | Inhibitor | [525703] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
PANTHER Pathway | DNA replication | ||||
Pathway Interaction Database | Caspase Cascade in Apoptosis | ||||
WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
References |
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