Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02COM
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| Former ID |
DNC000104
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| Drug Name |
7-tert-butyl-2, 3-dihydro-3, 3-dimethyl substituted dihydrofuran 30 (DHDMBF30)
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C24H34N2O4+2
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| Canonical SMILES |
C[N+]1(CCOC(C1)(C2=CC=C(C=C2)C3=CC=C(C=C3)C4(C[N+](CCO4<br />)(C)C)O)O)C
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| InChI |
1S/C24H34N2O4/c1-25(2)13-15-29-23(27,17-25)21-9-5-19(6-10-21)20-7-11-22(12-8-20)24(28)18-26(3,4)14-16-30-24/h5-12,27-28H,13-18H2,1-4H3/q+2
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| InChIKey |
JIWUESGGKYLPPG-UHFFFAOYSA-N
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| CAS Number |
CAS 16478-59-4
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| PubChem Compound ID | |||||
| PubChem Substance ID |
7440465, 8152261, 11466421, 11467541, 11486262, 26756595, 29222711, 47365421, 47365422, 47885612, 48185192, 48259465, 49698469, 49994532, 50070722, 50111083, 50381698, 57321877, 85209525, 90341031, 103107979, 103170774, 104303932, 114916412, 117613891, 124749826, 124880252, 128281574, 129212665, 134339628, 134339629, 134340080, 135073722, 136351306, 137008799, 141867156, 142312972, 160849790, 162800225, 178101222, 179236191, 237684190
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| Target and Pathway | |||||
| Target(s) | Arachidonate 5-lipoxygenase | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Aspirin-triggered lipoxin biosynthesis | ||||
| Resolvin D biosynthesis | |||||
| Leukotriene biosynthesis | |||||
| Lipoxin biosynthesis | |||||
| Aspirin triggered resolvin D biosynthesis | |||||
| Aspirin triggered resolvin E biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Ovarian steroidogenesis | |||||
| Toxoplasmosis | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Vitamin D Receptor Pathway | ||||
| Arachidonic acid metabolism | |||||
| Eicosanoid Synthesis | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
| REF 1 | Effect of 5-LOX/COX-2 common inhibitor DHDMBF30 on pancreatic cancer cell Capan2. World J Gastroenterol. 2008 Apr 28;14(16):2494-500. | ||||
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