Drug General Information
Drug ID	D02AVL
Drug Name	ZK-813039
Synonyms	DE-00684; Factor Xa inhibitor (oral), Schering AG/Pfizer; ZK-813039
Drug Type	Small molecular drug
Indication	Unspecified		Investigative	[528872]
Structure		Download 2D MOL 3D MOL
Formula	C23H19Cl3N6O3S
PubChem Compound ID	18376720
Target and Pathway
Target(s)	Coagulation factor Xa	Target Info	Modulator	[528872]
KEGG Pathway	Complement and coagulation cascades
PANTHER Pathway	Blood coagulation
Pathway Interaction Database	Beta2 integrin cell surface interactions
PathWhiz Pathway	Coagulation
Reactome	Extrinsic Pathway of Fibrin Clot Formation
	Intrinsic Pathway of Fibrin Clot Formation
	Common Pathway of Fibrin Clot Formation
	Gamma-carboxylation of protein precursors
	Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
	Removal of aminoterminal propeptides from gamma-carboxylated proteins
WikiPathways	Complement and Coagulation Cascades
	Human Complement System
	PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
	Blood Clotting Cascade
	Formation of Fibrin Clot (Clotting Cascade)
References
Ref 528872	J Med Chem. 2007 Jun 28;50(13):2967-80. Epub 2007 May 31.Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.
Ref 528872	J Med Chem. 2007 Jun 28;50(13):2967-80. Epub 2007 May 31.Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.