| Drug General Information |
| Drug ID |
D02AVL
|
| Drug Name |
ZK-813039
|
| Synonyms |
DE-00684; Factor Xa inhibitor (oral), Schering AG/Pfizer; ZK-813039
|
| Drug Type |
Small molecular drug
|
| Indication |
Unspecified
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C23H19Cl3N6O3S
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Coagulation factor Xa |
Target Info |
Modulator |
[1]
|
|---|
|
KEGG Pathway
|
Complement and coagulation cascades
|
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PANTHER Pathway
|
Blood coagulation
|
|
Pathway Interaction Database
|
Beta2 integrin cell surface interactions
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|
PathWhiz Pathway
|
Coagulation
|
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Reactome
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Extrinsic Pathway of Fibrin Clot Formation
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Intrinsic Pathway of Fibrin Clot Formation
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Common Pathway of Fibrin Clot Formation
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Gamma-carboxylation of protein precursors
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Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
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Removal of aminoterminal propeptides from gamma-carboxylated proteins
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WikiPathways
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Complement and Coagulation Cascades
|
|
Human Complement System
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PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
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Blood Clotting Cascade
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Formation of Fibrin Clot (Clotting Cascade)
|
| References |
| REF 1 | J Med Chem. 2007 Jun 28;50(13):2967-80. Epub 2007 May 31.Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors. |
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