Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01XGX
|
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| Former ID |
DIB003724
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| Drug Name |
JTP-4819
|
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| Synonyms |
JTP-3399
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| Drug Type |
Small molecular drug
|
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| Indication | Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3] | Discontinued in Phase 2 | [1] | ||
| Company |
Japan Tobacco Inc
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| Structure |
|
Download2D MOL |
|||
| Formula |
C19H25N3O4
|
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| Canonical SMILES |
N1(C(=O)[C@H]2N(C(=O)NCc3ccccc3)CCC2)[C@H](C(=O)CO)CCC1
|
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| CAS Number |
CAS 162203-65-8
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Prolyl endopeptidase | Target Info | Modulator | [2] | |
| KEGG Pathway | Renin-angiotensin system | ||||
| PANTHER Pathway | Vasopressin synthesis | ||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006163) | ||||
| REF 2 | A novel prolyl endopeptidase inhibitor, JTP-4819, with potential for treating Alzheimer's disease. Behav Brain Res. 1997 Feb;83(1-2):147-51. | ||||
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