Drug Information
Drug General Information | |||||
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Drug ID |
D01WUA
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Former ID |
DAP001214
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Drug Name |
Treprostinil
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Synonyms |
Treprostinilo; Treprostinilum; Uniprost; Viveta; Treprostinil sodium; LRX 15; U 62840; Remodulin (TN); Treprostinil [USAN:INN]; UT-15; Treprostinil (USAN/INN); U-62,840; ((1R,2R,3aS,9aS)-2-hydroxy-1-((3S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cylopent(b)naphthalen-5-yl)oxy)acetate; ({(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl}oxy)acetic acid; 15 AU81; 2-[[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid; 2-[[(1S,2S,3aR,9aR)-2-hydroxy-1-[(3R)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antihypertensive Agents
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Structure |
Download2D MOL |
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Formula |
C23H34O5
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InChI |
InChI=1S/C23H34O5/c1-2-3-4-7-17(24)9-10-18-19-11-15-6-5-8-22(28-14-23(26)27)20(15)12-16(19)13-21(18)25/h5-6,8,16-19,21,24-25H,2-4,7,9-14H2,1H3,(H,26,27)/t16-,17-,18+,19-,21+/m0/s1
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InChIKey |
PAJMKGZZBBTTOY-ZFORQUDYSA-N
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CAS Number |
CAS 81846-19-7
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PubChem Compound ID | |||||
PubChem Substance ID |
14854155, 14878554, 23950807, 43529534, 46504572, 47207871, 50304326, 56394875, 57371812, 114787499, 128887520, 134224636, 135014308, 136933659, 137249659, 143205120, 162205084, 163138465, 164234753, 170467450, 174548947, 175265596, 178102445, 179117156, 223938513, 230287018, 250136886, 252356445, 252457273, 252469194
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ChEBI ID |
ChEBI:50861
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SuperDrug ATC ID |
B01AC21
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Target and Pathway | |||||
Target(s) | Prostacyclin receptor | Target Info | Agonist | [537188] | |
Pathway Interaction Database | Thromboxane A2 receptor signaling | ||||
References | |||||
Ref 536294 | Emerging treatments for pulmonary arterial hypertension. Expert Opin Emerg Drugs. 2006 Nov;11(4):609-19. | ||||
Ref 541139 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5820). |
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