Drug General Information
Drug ID
D01VDB
Former ID
DNC000741
Drug Name
Howiinol A (GHM-10)
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535138]
Structure
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2D MOL

3D MOL

Formula
C22H20O6
Canonical SMILES
C1=CC=C(C=C1)C=CC(=O)OC(C2=CC=CC=C2)C(C3C(C=CC(=O)O3)O)<br />O
InChI
1S/C22H20O6/c23-17-12-14-19(25)28-22(17)20(26)21(16-9-5-2-6-10-16)27-18(24)13-11-15-7-3-1-4-8-15/h1-14,17,20-23,26H/b13-11+/t17-,20+,21+,22+/m0/s1
InChIKey
HCJURVKKVSCZRL-VTWBULIDSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) DNA topoisomerase II Target Info Inhibitor [535138]
References
Ref 535138Anticancer effect of Howiinol A and its mechanism of action. J Asian Nat Prod Res. 1999;2(1):1-19.
Ref 535138Anticancer effect of Howiinol A and its mechanism of action. J Asian Nat Prod Res. 1999;2(1):1-19.

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