Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01RGM
|
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| Former ID |
DNC002492
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| Drug Name |
S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C10H12ClF3N2S
|
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| Canonical SMILES |
CCSC(=NC1=CC=C(C=C1)C(F)(F)F)N.Cl
|
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| InChI |
1S/C10H11F3N2S.ClH/c1-2-16-9(14)15-8-5-3-7(4-6-8)10(11,12)13;/h3-6H,2H2,1H3,(H2,14,15);1H
|
||||
| InChIKey |
UVJQIYZYQQKIAC-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Nitric-oxide synthase, brain | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Citrulline-nitric oxide cycle | ||||
| KEGG Pathway | Arginine and proline metabolism | ||||
| Metabolic pathways | |||||
| Calcium signaling pathway | |||||
| Phagosome | |||||
| Circadian entrainment | |||||
| Long-term depression | |||||
| Salivary secretion | |||||
| Alzheimer's disease | |||||
| Amyotrophic lateral sclerosis (ALS) | |||||
| NetPath Pathway | EGFR1 Signaling Pathway | ||||
| PANTHER Pathway | CCKR signaling map ST | ||||
| PathWhiz Pathway | Arginine and Proline Metabolism | ||||
| Reactome | ROS production in response to bacteria | ||||
| Nitric oxide stimulates guanylate cyclase | |||||
| WikiPathways | Monoamine Transport | ||||
| Myometrial Relaxation and Contraction Pathways | |||||
| Amyotrophic lateral sclerosis (ALS) | |||||
| Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | |||||
| Spinal Cord Injury | |||||
| Alzheimers Disease | |||||
| Effects of Nitric Oxide | |||||
| Serotonin Transporter Activity | |||||
| References | |||||
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | ||||
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