Drug Information
Drug General Information | |||||
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Drug ID |
D01OYS
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Former ID |
DIB002788
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Drug Name |
Cyclolignan picropodophyllin
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Synonyms |
PPP; IGF-1R inhibitor (cancer), Karolinska
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Indication | Colorectal cancer [ICD9: 153, 154; ICD10:C18-C21] | Phase 1 | [544191] | ||
Company |
Karolinska Institute
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Target and Pathway | |||||
Target(s) | Insulin-like growth factor I receptor | Target Info | Inhibitor | [528935] | |
KEGG Pathway | Ras signaling pathway | ||||
Rap1 signaling pathway | |||||
HIF-1 signaling pathway | |||||
FoxO signaling pathway | |||||
Oocyte meiosis | |||||
Endocytosis | |||||
PI3K-Akt signaling pathway | |||||
AMPK signaling pathway | |||||
Focal adhesion | |||||
Adherens junction | |||||
Signaling pathways regulating pluripotency of stem cells | |||||
Long-term depression | |||||
Ovarian steroidogenesis | |||||
Progesterone-mediated oocyte maturation | |||||
Pathways in cancer | |||||
Transcriptional misregulation in cancer | |||||
Proteoglycans in cancer | |||||
Glioma | |||||
Prostate cancer | |||||
Melanoma | |||||
References |
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