Drug Information

Drug General Information
Drug ID
D01LFP
Former ID
DNC013209
Drug Name
N1-(4-chlorobenzyl)-2-benzyl-N3-hydroxymalonamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528703]
Structure
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2D MOL

3D MOL
Formula
C17H17ClN2O3
Canonical SMILES
C1=CC=C(C=C1)CC(C(=O)NCC2=CC=C(C=C2)Cl)C(=O)NO
InChI
1S/C17H17ClN2O3/c18-14-8-6-13(7-9-14)11-19-16(21)15(17(22)20-23)10-12-4-2-1-3-5-12/h1-9,15,23H,10-11H2,(H,19,21)(H,20,22)
InChIKey
MDFALTKCDXYVEX-UHFFFAOYSA-N
PubChem Compound ID
16114883
Target and Pathway
Target(s) Aminopeptidase N Target Info Inhibitor [528703]
BioCyc Pathway Glutathione-mediated detoxification
KEGG Pathway Glutathione metabolism
Metabolic pathways
Renin-angiotensin system
Hematopoietic cell lineage
Pathway Interaction Database C-MYB transcription factor network
PathWhiz Pathway Glutathione Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways Metabolism of Angiotensinogen to Angiotensins
Cardiac Progenitor Differentiation
miR-targeted genes in squamous cell - TarBase
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
Glutathione metabolism
References
Ref 528703J Med Chem. 2007 Mar 22;50(6):1322-34. Epub 2007 Feb 28.Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents.
Ref 528703J Med Chem. 2007 Mar 22;50(6):1322-34. Epub 2007 Feb 28.Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents.

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