Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01LAU
|
||||
| Former ID |
DNC008529
|
||||
| Drug Name |
5-methoxycarbonylamino-N-acetyltryptamine
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C14H17N3O3
|
||||
| InChI |
InChI=1S/C14H17N3O3/c1-9(18)15-6-5-10-8-16-13-4-3-11(7-12(10)13)17-14(19)20-2/h3-4,7-8,16H,5-6H2,1-2H3,(H,15,18)(H,17,19)
|
||||
| InChIKey |
MPZVHKLZCUEJFO-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID |
6290404, 7978608, 9627826, 11113768, 14750699, 26751952, 29215031, 35542592, 47583802, 48329131, 57356892, 71753364, 79639898, 85787577, 91614382, 103619802, 104110036, 112845218, 123050766, 128631352, 134221808, 134345734, 135698167, 137186245, 142405033, 162022746, 162247320, 162967835, 164761931, 178100406, 184594788, 204371613, 223759866, 230562864, 241181962, 241377516, 249776595
|
||||
| Target and Pathway | |||||
| Target(s) | Melatonin receptor type 1B | Target Info | Inhibitor | [2] | |
| Melatonin receptor | Target Info | Inhibitor | [2] | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Circadian entrainmenthsa04080:Neuroactive ligand-receptor interaction | |||||
| Circadian entrainment | |||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors) | |||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Small Ligand GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3393). | ||||
| REF 2 | Bioorg Med Chem. 2008 May 1;16(9):4954-62. Epub 2008 Mar 17.Design and synthesis of benzofuranic derivatives as new ligands at the melatonin-binding site MT3. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.