Drug General Information
Drug ID	D01KOO
Former ID	DNC006641
Drug Name	(2,2-dimethyl-1,3-dioxolan-4-yl)methyl sulfamate
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528233]
Structure		Download 2D MOL 3D MOL
Formula	C6H13NO5S
Canonical SMILES	CC1(OCC(O1)COS(=O)(=O)N)C
InChI	1S/C6H13NO5S/c1-6(2)10-3-5(12-6)4-11-13(7,8)9/h5H,3-4H2,1-2H3,(H2,7,8,9)
InChIKey	QFFBTRPNKKXQCZ-UHFFFAOYSA-N
PubChem Compound ID	13654029
Target and Pathway
Target(s)	Carbonic anhydrase II	Target Info	Inhibitor	[528233]
KEGG Pathway	Nitrogen metabolism
	Proximal tubule bicarbonate reclamation
	Collecting duct acid secretion
	Gastric acid secretion
	Pancreatic secretion
	Bile secretion
NetPath Pathway	IL4 Signaling Pathway
	EGFR1 Signaling Pathway
Reactome	Erythrocytes take up carbon dioxide and release oxygen
	Erythrocytes take up oxygen and release carbon dioxide
	Reversible hydration of carbon dioxide
WikiPathways	Reversible Hydration of Carbon Dioxide
	Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
	Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
References
Ref 528233	J Med Chem. 2006 Jun 15;49(12):3496-500.Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements.
Ref 528233	J Med Chem. 2006 Jun 15;49(12):3496-500.Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements.

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