Drug General Information
Drug ID
D01JJH
Former ID
DIB018080
Drug Name
(3R,4S)-293B
Synonyms
LS-185874; chromanol 239B
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526219]
Structure
Download
2D MOL
Formula
C15H20N2O4S
InChI
InChI=1S/C15H20N2O4S/c1-5-22(19,20)17(4)13-11-8-10(9-16)6-7-12(11)21-15(2,3)14(13)18/h6-8,13-14,18H,5H2,1-4H3/t13-,14+/m0/s1
InChIKey
HVSJHHXUORMCGK-UONOGXRCSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily KQT member 1 Target Info Blocker (channel blocker) [526219]
KEGG Pathway Adrenergic signaling in cardiomyocytes
Cholinergic synapse
Gastric acid secretion
Pancreatic secretion
Protein digestion and absorption
Vibrio cholerae infection
PathWhiz Pathway Muscle/Heart Contraction
Reactome Voltage gated Potassium channels
WikiPathways SIDS Susceptibility Pathways
Potassium Channels
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
TarBasePathway
References
Ref 526219A kinetic study on the stereospecific inhibition of KCNQ1 and I(Ks) by the chromanol 293B. Br J Pharmacol. 2001 Dec;134(8):1647-54.
Ref 526219A kinetic study on the stereospecific inhibition of KCNQ1 and I(Ks) by the chromanol 293B. Br J Pharmacol. 2001 Dec;134(8):1647-54.

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