Drug General Information
Drug ID
D01GTB
Former ID
DIB000005
Drug Name
ZD-2767
Synonyms
Colorectal cancer therapy (ADEPT), AstraZeneca/CRCT; Colorectal cancer therapy (ADEPT), Zeneca/CRCT
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Discontinued in Phase 1 [545723]
Company
AstraZeneca plc
Structure
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2D MOL

3D MOL

Canonical SMILES
C(=O)(N[C@H](C(=O)O)CCC(=O)O)Oc1ccc(N(CCI)CCI)cc1
CAS Number
CAS 156079-88-8
Target and Pathway
Target(s) Human DNA Target Info Binder [544052]
References
Ref 545723Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004376)
Ref 544052Induction of apoptosis by the ADEPT agent ZD2767: comparison with the classical nitrogen mustard chlorambucil and a monofunctional ZD2767 analogue. Br J Cancer. 2001 September; 85(5): 764-771.

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