Drug Information

Drug General Information
Drug ID
D01AZP
Former ID
DIB013712
Drug Name
BNC-105
Synonyms
BNC-105P; IL-0035; IL-0049; Combretastatin A4 analogs (cancer), Bionomics; VDAs (cancer), Bionomics; Vascular disruption agents (cancer), Bionomics; Vascular targeting agents (cancer), Bionomics
Drug Type
Small molecular drug
Indication Mesothelioma [ICD9: 163; ICD10:C45] Phase 2 [547995]
Company
Iliad Chemicals Pty Ltd
Structure
Download
2D MOL

3D MOL
Formula
C20H20O7
Canonical SMILES
c1(ccc2c(c1OP(=O)([O-])[O-])oc(c2C(=O)c1cc(c(c(c1)OC)OC<br />)OC)C)OC.[Na+].[Na+]
PubChem Compound ID
24786555
Target and Pathway
Target(s) Tubulin beta Target Info Modulator
KEGG Pathway Phagosome
Gap junction
Pathogenic Escherichia coli infection
NetPath Pathway FSH Signaling Pathway
TCR Signaling Pathway
EGFR1 Signaling Pathway
PANTHER Pathway Cytoskeletal regulation by Rho GTPase
Huntington disease
Reactome Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization?from the centrosome
Anchoring of the basal body to the plasma membrane
WikiPathways Parkin-Ubiquitin Proteasomal System pathway
Pathogenic Escherichia coli infection
Mitotic G2-G2/M phases
References
Ref 547995Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021025)

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