TTD | Drug: D00ZMS

Drug General Information
Drug ID	D00ZMS
Former ID	DNC013545
Drug Name	1-(but-2-ylamino)ethyl 1,I-bisphosphonic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529229]
Structure		Download 2D MOL 3D MOL
Formula	C6H17NO6P2
Canonical SMILES	CCC(C)NCC(P(=O)(O)O)P(=O)(O)O
InChI	1S/C6H17NO6P2/c1-3-5(2)7-4-6(14(8,9)10)15(11,12)13/h5-7H,3-4H2,1-2H3,(H2,8,9,10)(H2,11,12,13)
InChIKey	BDBDLQIJTHDVGZ-UHFFFAOYSA-N
PubChem Compound ID	44451344
Target and Pathway
Target(s)	Farnesyl pyrophosphatesynthetase	Target Info	Inhibitor	[529229]
KEGG Pathway	Terpenoid backbone biosynthesis
	Metabolic pathways
	Biosynthesis of antibiotics
	Influenza A
	HTLV-I infection
PathWhiz Pathway	Steroid Biosynthesis
Reactome	Cholesterol biosynthesis
Reactome	Activation of gene expression by SREBF (SREBP)
WikiPathways	Activation of Gene Expression by SREBP (SREBF)
	SREBP signalling
	Cholesterol Biosynthesis
References
Ref 529229	Bioorg Med Chem. 2008 Mar 15;16(6):3283-90. Epub 2007 Dec 10.Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase.
Ref 529229	Bioorg Med Chem. 2008 Mar 15;16(6):3283-90. Epub 2007 Dec 10.Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase.

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Drug Information