Drug Information
Drug General Information | |||||
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Drug ID |
D00ZGA
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Former ID |
DCL000741
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Drug Name |
Casopitant
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Synonyms |
Rezonic; Zunrisa; GW 679769; GW679769
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Drug Type |
Small molecular drug
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Company |
GlaxoSmithKline
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Structure |
Download2D MOL |
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Formula |
C30H35F7N4O2
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InChI |
InChI=1S/C30H35F7N4O2/c1-18-13-24(31)5-6-26(18)27-17-25(40-11-9-39(10-12-40)20(3)42)7-8-41(27)28(43)38(4)19(2)21-14-22(29(32,33)34)16-23(15-21)30(35,36)37/h5-6,13-16,19,25,27H,7-12,17H2,1-4H3/t19-,25+,27-/m1/s1
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InChIKey |
XGGTZCKQRWXCHW-WMTVXVAQSA-N
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CAS Number |
CAS 414910-30-8
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Substance-P receptor | Target Info | Antagonist | [536580] | |
PANTHER Pathway | CCKR signaling map ST | ||||
Reactome | G alpha (q) signalling events | ||||
References | |||||
Ref 536580 | Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology. 2008 Aug;33(9):2080-92. Epub 2008 Jan 2. | ||||
Ref 541092 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5758). |
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