Drug Information

Drug General Information
Drug ID
D00YLM
Former ID
DIB007508
Drug Name
TRAXOPRODIL MESYLATE
Synonyms
Prop INNM >; Traxoprodil mesylate < USAN; CP-101606-27; (S,S)-1-(4-Hydroxyphenyl)-2-[4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol methanesulfonate trihydrate
Drug Type
Small molecular drug
Indication Neurological disease [ICD9: 338, 338.2, 410, 782.3,780; ICD10:I21, I22, R52, R52.1-R52.2, R60.9, G89] Phase 2 [521688]
Structure
Download
2D MOL

3D MOL
Formula
C21H29NO6S
Canonical SMILES
C[C@@H]([C@@H](O)c1ccc(O)cc1)N2CCC(O)(CC2)c3ccccc3
InChI
1S/C20H25NO3/c1-15(19(23)16-7-9-18(22)10-8-16)21-13-11-20(24,12-14-21)17-5-3-2-4-6-17/h2-10,15,19,22-24H,11-14H2,1H3/t15-,19+/m0/s1
InChIKey
QEMSVZNTSXPFJA-HNAYVOBHSA-N
PubChem Compound ID
9802399
Target and Pathway
Target(s) NMDA receptor Target Info Modulator [527945], [551871]
References
Ref 521688ClinicalTrials.gov (NCT00163059) The Antidepressant Effects Of The NMDA Antagonist, CP-101,606, In Patients With MDD. U.S. National Institutes of Health.
Ref 527945J Neurotrauma. 2005 Dec;22(12):1428-43.The effect of the selective NMDA receptor antagonist traxoprodil in the treatment of traumatic brain injury.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.