Drug General Information
Drug ID	D00XMO
Former ID	DNC009753
Drug Name	2-(4-chlorobenzylidene)cyclopentyl ethyl ether
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529980]
Structure		Download 2D MOL 3D MOL
Formula	C14H17ClO
Canonical SMILES	CCOC1CCCC1=CC2=CC=C(C=C2)Cl
InChI	1S/C14H17ClO/c1-2-16-14-5-3-4-12(14)10-11-6-8-13(15)9-7-11/h6-10,14H,2-5H2,1H3/b12-10+
InChIKey	VORGMCXCJIDOMV-ZRDIBKRKSA-N
PubChem Compound ID	44126813
Target and Pathway
Target(s)	Aldo-keto reductase family 1 member C3	Target Info	Inhibitor	[529980]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Allopregnanolone biosynthesis
	Androgen biosynthesis
KEGG Pathway	Steroid hormone biosynthesis
	Arachidonic acid metabolism
	Metabolic pathways
	Ovarian steroidogenesis
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
Reactome	Retinoid metabolism and transport
WikiPathways	Metapathway biotransformation
	Benzo(a)pyrene metabolism
	Arachidonic acid metabolism
References
Ref 529980	Eur J Med Chem. 2009 Jun;44(6):2563-71. Epub 2009 Feb 5.New cyclopentane derivatives as inhibitors of steroid metabolizing enzymes AKR1C1 and AKR1C3.
Ref 529980	Eur J Med Chem. 2009 Jun;44(6):2563-71. Epub 2009 Feb 5.New cyclopentane derivatives as inhibitors of steroid metabolizing enzymes AKR1C1 and AKR1C3.

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