TTD | Drug: D00WHO

Drug General Information
Drug ID	D00WHO
Former ID	DNC014568
Drug Name	Ro-15-3505
Synonyms	Sarmazenil
Drug Type	Small molecular drug
Indication	Discovery agent		Terminated	[546017]
Structure		Download 2D MOL 3D MOL
Formula	C15H14ClN3O3
Canonical SMILES	CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)Cl)C
InChI	1S/C15H14ClN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3
InChIKey	QORLMYYHZLDYOR-UHFFFAOYSA-N
CAS Number	CAS 78771-13-8
PubChem Compound ID	114888
Target and Pathway
Target(s)	GABA A receptor	Target Info	Modulator
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
Reactome	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 546017	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005900)

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Drug Information