Drug Information
Drug General Information | |||||
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Drug ID |
D00VMA
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Former ID |
DIB014504
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Drug Name |
Vatreptacog alfa (activated)
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Synonyms |
NN-1731; NNC-0078-0000-0007; Recombinant factor VIIa analog with mutations V158D/E296V/M298Q (bleeding disorders), Novo Nordisk
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Indication | Bleeding [ICD9: 444, 453; ICD10:I74, I80-I82] | Phase 3 | [523543] | ||
Company |
Novo Nordisk A/S
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Target and Pathway | |||||
Target(s) | Coagulation factor VII | Target Info | Modulator | [531867] | |
KEGG Pathway | Complement and coagulation cascades | ||||
PANTHER Pathway | Angiogenesis | ||||
Blood coagulation | |||||
PathWhiz Pathway | Coagulation | ||||
Reactome | BMAL1:CLOCK,NPAS2 activates circadian gene expression | ||||
Extrinsic Pathway of Fibrin Clot Formation | |||||
Gamma-carboxylation of protein precursors | |||||
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
References |
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