Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00RJB
|
||||
| Former ID |
DIB014546
|
||||
| Drug Name |
Rilopirox
|
||||
| Synonyms |
Riloprox; Hoe-351
|
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| Drug Type |
Small molecular drug
|
||||
| Indication | Fungal infections [ICD9: 110-118; ICD10:B35-B49] | Phase 2 | [1] | ||
| Company |
Hoechst AG
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C19H16ClNO4
|
||||
| Canonical SMILES |
n1(c(cc(cc1=O)C)COc1ccc(Oc2ccc(Cl)cc2)cc1)O
|
||||
| CAS Number |
CAS 104153-37-9
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 5-lipoxygenase | Target Info | Inhibitor | [2] | |
| BioCyc Pathway | Aspirin-triggered lipoxin biosynthesis | ||||
| Resolvin D biosynthesis | |||||
| Leukotriene biosynthesis | |||||
| Lipoxin biosynthesis | |||||
| Aspirin triggered resolvin D biosynthesis | |||||
| Aspirin triggered resolvin E biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Ovarian steroidogenesis | |||||
| Toxoplasmosis | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| WikiPathways | Vitamin D Receptor Pathway | ||||
| Arachidonic acid metabolism | |||||
| Eicosanoid Synthesis | |||||
| Selenium Micronutrient Network | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006112) | ||||
| REF 2 | Therapy of seborrheic eczema with an antifungal agent with an antiphlogistic effect. Mycoses. 1991;34 Suppl 1:91-3. | ||||
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