Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00QCL
|
||||
| Former ID |
DNC012026
|
||||
| Drug Name |
SOPHOFLAVESCENOL
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C21H20O6
|
||||
| Canonical SMILES |
CC(=CCC1=C(C=C(C2=C1OC(=C(C2=O)O)C3=CC=C(C=C3)O)OC)O)C
|
||||
| InChI |
1S/C21H20O6/c1-11(2)4-9-14-15(23)10-16(26-3)17-18(24)19(25)20(27-21(14)17)12-5-7-13(22)8-6-12/h4-8,10,22-23,25H,9H2,1-3H3
|
||||
| InChIKey |
VMLJAWUWVVHRNG-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | CAMP-specific 3',5'-cyclic phosphodiesterase 4A | Target Info | Inhibitor | [1] | |
| CGMP-specific 3',5'-cyclic phosphodiesterase | Target Info | Inhibitor | [1] | ||
| CGMP-inhibited 3',5'-cyclic phosphodiesterase A | Target Info | Inhibitor | [1] | ||
| CAMP-specific 3',5'-cyclic phosphodiesterase 4B | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Purine metabolism | ||||
| cAMP signaling pathway | |||||
| Morphine addictionhsa00230:Purine metabolism | |||||
| cGMP-PKG signaling pathwayhsa00230:Purine metabolism | |||||
| cGMP-PKG signaling pathway | |||||
| Morphine addiction | |||||
| NetPath Pathway | TGF_beta_Receptor Signaling PathwayNetPath_17:IL5 Signaling Pathway | ||||
| IL2 Signaling Pathway | |||||
| Reactome | DARPP-32 events | ||||
| G alpha (s) signalling eventsR-HSA-418457:cGMP effectsR-HSA-418457:cGMP effects | |||||
| G alpha (s) signalling eventsR-HSA-180024:DARPP-32 events | |||||
| G alpha (s) signalling events | |||||
| WikiPathways | G Protein Signaling PathwaysWP2005:miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBaseWP35:G Protein Signaling Pathways | |||||
| Myometrial Relaxation and Contraction Pathways | |||||
| Nuclear Receptors Meta-Pathway | |||||
| Opioid Signalling | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2002 Sep 2;12(17):2313-6.A prenylated flavonol, sophoflavescenol: a potent and selective inhibitor of cGMP phosphodiesterase 5. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.