Drug Information

Drug General Information
Drug ID
D00KCB
Former ID
DNC002722
Drug Name
Fidarestat(Stereoisomer)
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C12H10FN3O4
Canonical SMILES
C1C(OC2=C(C13C(=O)NC(=O)N3)C=C(C=C2)F)C(=O)N
InChI
1S/C12H10FN3O4/c13-5-1-2-7-6(3-5)12(4-8(20-7)9(14)17)10(18)15-11(19)16-12/h1-3,8H,4H2,(H2,14,17)(H2,15,16,18,19)/t8-,12+/m1/s1
InChIKey
WAAPEIZFCHNLKK-PELKAZGASA-N
PubChem Compound ID
449156
PubChem Substance ID
584770, 7887489, 36890814, 46505893, 46506217, 58107139, 77292492, 103286615, 103988190, 104640519, 137165212, 160965243, 226432693, 243477353
Target and Pathway
Target(s) Aldose reductase Target Info Inhibitor [551393]
BioCyc Pathway Methylglyoxal degradation III
Acetone degradation I (to methylglyoxal)
KEGG Pathway Pentose and glucuronate interconversions
Fructose and mannose metabolism
Galactose metabolism
Glycerolipid metabolism
Metabolic pathways
NetPath Pathway IL1 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Fructose and Mannose Degradation
Pyruvate Metabolism
Pterine Biosynthesis
Glycerolipid Metabolism
Galactose Metabolism
WikiPathways Metapathway biotransformation
Polyol Pathway
Metabolism of steroid hormones and vitamin D
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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