Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D00AWT
|
||||
Former ID |
DAP000413
|
||||
Drug Name |
Propericiazine
|
||||
Synonyms |
Aolept; Nemactil; Neulactil; Neuleptil; PERICYAZINE; Periciazina; Periciazine; Periciazinum; Piperocyanomazine;Periciazine [INN]; Bayer 1409; IC 6002; RP 8908; WH 7508; Neulactil (TN); Neuleptil (TN); Periciazina [INN-Spanish]; Periciazinum [INN-Latin]; Propericiazine (JAN); Propericiazine(jan); SKF 20,716; Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine; Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine [French]; 10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile; 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile; 10-[3-(4-hydroxypiperidin-1-yl)propyl]phenothiazine-2-carbonitrile; 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine; 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine; 6909 RP
|
||||
Drug Type |
Small molecular drug
|
||||
Therapeutic Class |
Antipsychotic Agents
|
||||
Company |
Sanofi-Aventis
|
||||
Structure |
Download2D MOL |
||||
Formula |
C21H23N3OS
|
||||
Canonical SMILES |
C1CN(CCC1O)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C#N
|
||||
InChI |
1S/C21H23N3OS/c22-15-16-6-7-21-19(14-16)24(18-4-1-2-5-20(18)26-21)11-3-10-23-12-8-17(25)9-13-23/h1-2,4-7,14,17,25H,3,8-13H2
|
||||
InChIKey |
LUALIOATIOESLM-UHFFFAOYSA-N
|
||||
CAS Number |
CAS 2622-26-6
|
||||
PubChem Compound ID | |||||
PubChem Substance ID |
7703132, 7848548, 7980281, 8150082, 8152913, 10516133, 11336049, 11361288, 11364508, 11367070, 11369632, 11371656, 11373958, 11377794, 11462260, 11485343, 11489420, 11490564, 11492025, 11495428, 14803709, 26612557, 26680430, 26748871, 26748872, 29223833, 46505085, 47291188, 47810806, 48259291, 50006266, 50107474, 56464150, 57322425, 79997266, 85789600, 92124822, 99301962, 103555929, 103846500, 104307313, 117515052, 124636904, 126673224, 128541428, 131349353, 134224641, 134337709, 134982092, 136913034
|
||||
ChEBI ID |
ChEBI:31981
|
||||
SuperDrug ATC ID |
N05AC01
|
||||
SuperDrug CAS ID |
cas=002622266
|
||||
Target and Pathway | |||||
Target(s) | Alpha-1B adrenergic receptor | Target Info | Binder | [537783] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
PANTHER Pathway | Alpha adrenergic receptor signaling pathway | ||||
Pathway Interaction Database | LPA receptor mediated events | ||||
References | |||||
Ref 533807 | Affinity of neuroleptics for D1 receptor of human brain striatum. J Psychiatry Neurosci. 1994 Jul;19(4):265-9. | ||||
Ref 537783 | Interaction of neuroleptics and antidepressants with rat brain alpha 2-receptors: a possible relationship between alpha 2-receptor antagonism and antidepressant action. Biol Psychiatry. 1984 Sep;19(9):1283-91. | ||||
Ref 551439 | Drug Information of Troleandomycin from nextbio research in illumina. 2015. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.