Target Information

Target General Infomation
Target ID
T92138
Former ID
TTDC00315
Target Name
Phosphodiesterase
Target Type
Clinical Trial
Disease Angina pectoris [ICD9: 413; ICD10: I20]
Target Validation
T92138
UniProt ID
Q08497
Sequence
RPRGLGRIPELQLVAFPVAVAAEDEAFLPEPLAPRAPRRPRSPPSSPVFFASPSPTFRRR
LRLLRSCQDLGRQAWAGAGFEAENGPTPSPGRSPLDSQASPGLVLHAGAPPASAGSPSCT
AQTATMTCHPRPCPGTHRSPAR
Drugs and Mode of Action
Drug(s) NM-702 Drug Info Phase 3 Angina pectoris [544180]
Inhibitor NM-702 Drug Info [536325]
References
Ref 544180Application of adaptive design and decision making to a phase II trial of a phosphodiesterase inhibitor for the treatment of intermittent claudication. Trials. 2011; 12: 134.
Ref 536325The novel phosphodiesterase inhibitor NM-702 improves claudication-limited exercise performance in patients with peripheral arterial disease. J Am Coll Cardiol. 2006 Dec 19;48(12):2539-45. Epub 2006Nov 28.
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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