Target General Infomation
Target ID
T75655
Former ID
TTDR00441
Target Name
Apolipoprotein A-II
Gene Name
APOA2
Synonyms
Apo-AII; ApoA-II; APOA2
Target Type
Research
Function
May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
BioChemical Class
Apolipoprotein
UniProt ID
Sequence
MKLLAATVLLLTICSLEGALVRRQAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAE
AKSYFEKSKEQLTPLIKKAGTELVNFLSYFVELGTQPATQ
Inhibitor B-Octylglucoside Drug Info [551393]
Pathways
KEGG Pathway PPAR signaling pathway
Reactome Chylomicron-mediated lipid transport
PPARA activates gene expression
Retinoid metabolism and transport
WikiPathways Complement and Coagulation Cascades
Statin Pathway
Nuclear Receptors Meta-Pathway
PPAR Alpha Pathway
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Visual phototransduction
Lipid digestion, mobilization, and transport
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.